Corneal Cross-Linking (CXL)
A revolutionary treatment to halt the progression of Keratoconus.
By Keratomania | October 15, 2025 | 6 min read
Corneal Cross-Linking, often abbreviated as CXL, is a minimally invasive procedure designed to strengthen the cornea and stop Keratoconus from getting worse. It is the only treatment currently available that can halt the progression of the disease.
How Does CXL Work?
The procedure works by creating new chemical bonds between the collagen fibers within the cornea. These fibers are the natural anchors that help the cornea maintain its shape. The process involves:
- Applying riboflavin (vitamin B2) eye drops to the cornea.
- Exposing the cornea to a controlled amount of ultraviolet A (UVA) light.
The riboflavin acts as a photosensitizer, and when activated by the UVA light, it forms strong new links between the collagen fibers. This stiffens the cornea, making it more stable and preventing further bulging.
Who is a Good Candidate for CXL?
CXL is most effective for patients with progressive Keratoconus. An eye doctor will use corneal topography to confirm that the shape of the cornea is continuing to change. It is generally recommended for younger patients, as the cornea naturally stiffens with age.
While CXL does not typically reverse the changes that have already occurred, it is highly effective at preventing further vision loss. After the procedure, patients will still need glasses or contact lenses to achieve clear vision.